Total Diet Studies is intended to introduce the total diet study (TDS) concept to those involved in assuring the safety of the food supply from chemical risks (e.g., government agencies and the food industry) as well as to a wider audience of interested parties (e.g., development agencies and consumer organizations). It presents the various steps in the planning and implementation of a TDS and illustrates how TDSs are being used to protect public health from the potential risks posed by chemicals in the food supply in both developed and developing countries. The book also examines some of the applications of TDSs to specific chemicals, including contaminants and nutrients. The goal of a TDS is to provide baseline information on levels and trends of exposure to chemicals in foods as consumed by the population. In other words, foods are processed and prepared as typically consumed before they are analyzed in order to best represent actual dietary intakes., Total diet studies have been used to assess the safe use of agricultural chemicals (e.g., pesticides, antibiotics), food additives (e.g., preservatives, sweetening agents), environmental contaminants (e.g., lead, arsenic, cadmium, radionuclides), processing contaminants (e.g., acrylamide, polycyclic aromatic hydrocarbons, chloropropanols), and natural contaminants (e.g., aflatoxins) by determining whether dietary exposures to these chemicals are within acceptable limits. Total diet studies can also be applied to certain nutrients where the goal is to assure intakes are not only below safe upper limits, but also above levels deemed necessary to maintain good health., International and national organizations, such as the World Health Organization, the European Food Safety Agency, and the US Food and Drug Administration recognize the TDS approach as one of the most cost-effective means of protecting consumers from chemicals in food, for providing essential information for managing food safety, including food standards, and for setting priorities for further investigation and intervention.